IRF9 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | interferon regulatory factor 9 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q00978 | | Иммуноген | Fusion protein of human IRF9 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | | Примечание | Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse heart tissue, Primary antibody: CSB-PA438294(IRF9 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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Наименование: IRF9 Antibody.