Объем | 100 мкл |
Синонимы | Potassium voltage-gated channel subfamily KQT member 4, Voltage-gated potassium channel subunit Kv7.4, Potassium channel subunit alpha KvLQT4, KQT-like 4, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P56696 |
Иммуноген | Synthesized peptide derived from C-terminal of human KCNQ4. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.<br/><br/>Kubisch C., Cell 96:437-446(1999).<br/>Gregory S.G., Nature 441:315-321(2006).<br/>Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000).<br/> <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEc cells, using KCNQ4 antibody.
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