GPER1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | G protein-coupled estrogen receptor 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q99527 | Иммуноген | Synthetic peptide of human GPER1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 | Примечание | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA934518(GPER1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-3: Human placenta tissue, HepG2 cells, A549 cells, Primary antibody: CSB-PA934518(GPER1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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