Объем | 100 мкл |
Синонимы | glycoprotein M6A |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P51674 |
Иммуноген | Fusion protein of human GPM6A |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA223691(GPM6A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA223691(GPM6A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 20 ?g, Lane: Human fetal brain tissue, Primary antibody: CSB-PA223691(GPM6A Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
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