Объем | 100 мкл |
Синонимы | growth factor receptor-bound protein 10 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13322 |
Иммуноген | Synthetic peptide of human GRB10 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,ELISA:1:1000-1:10000, IHC:1:25-1:100 |
Примечание | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA449091(GRB10 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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