KIT (Ab-936) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | KIT, CD117, SCFR, PBT, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P10721 | | Иммуноген | Peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)<br/><br/>Martin, F.H. et al. (1990) Cell 63, 203-11.<br/>Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62.<br/>Gommerman, J.L. et al. (1997) J Biol Chem 272, 30519-25.<br/>Nocka, K. et al. (1990) EMBO J 9, 1805-13.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Cancer,Developmental biology,Tags & Cell Markers,Immunology,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HL60 cells using c-kit(Ab-936) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-kit(Ab-936) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: KIT (Ab-936) Antibody.