| Объем | 100 мкл |
| Синонимы | Kelch-like protein 3, KIAA1129, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UH77/Q8N4I8 |
| Иммуноген | Synthesized peptide derived from N-terminal of human KLHL3. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.<br/><br/>Lai F., Genomics 66:65-75(2000).<br/>Hirosawa M., DNA Res. 6:329-336(1999).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from RAW264.7 cells and 3T3 cells, using KLHL3 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLHL3 antibody.
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Immunofluorescence analysis of A549 cells, using KLHL3 antibody.
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Наименование: KLHL3 Antibody.