Kng1 AntibodyСпецификацияОбъем | 100 мкг | Синонимы | Kininogen-1 [Cleaved into: Kininogen-1 heavy chain, Bradykinin, Kininogen-1 light chain], Kng1, Kng | Клональность | Polyclonal Antibody | Организм | Rat | uniprot | P08934 | Иммуноген | Recombinant Rat Kininogen-1 protein (2-110AA) | Источник | Rabbit | Видовая специфичность | Rat | Применение | ELISA | Примечание | Kininogens are inhibitors of thiol proteases, (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes, (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action), (5) LMW-kininogen inhibits the aggregation of thrombocytes, (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Kininogen-1 | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказа |