GRIK1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | EAA3, EEA3, GLR5, GLUTAMATE RECEPTOR 5, excitatory amino acid receptor 3 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P39086 | | Иммуноген | Synthesized peptide derived from human GluR5. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.<br/><br/>Ana V. Paternain, J. Neurosci., Jan 2000, 20: 196.<br/>Zhao Ren, J. Biol. Chem., Dec 2003, 278: 52700 - 52709.<br/>MICHAEL A. ROGAWSKI, Ann. N.Y. Acad. Sci., Apr 2003, 985: 150.<br/>Yoshinori Sahara, J. Neurosci., Sep 1997, 17: 6611.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR5 antibody.
 | Western blot analysis of extracts from mouse brain, using GluR5 antibody.
 | Western blot analysis of extracts from HepG2 cells (Lane 2), using GluR5 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: GRIK1 Antibody.