Объем | 100 мкл |
Синонимы | HMG box-containing protein 1, HMG box-containing protein 1, High mobility group box transcription factor 1, HBP1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O60381 |
Иммуноген | Synthesized peptide derived from Internal of human HBP1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<br/><br/>Lemercier C., Mol. Cell. Biol. 20:6627-6637(2000).<br/>Hillier L.W., Nature 424:157-164(2003).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.
|
| |