HDAC3 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | histone deacetylase 3 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O15379 | Иммуноген | Synthetic peptide of human HDAC3 | Источник | Rabbit | Видовая специфичность | Human, Rat | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | Примечание | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Metabolism,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Raji cells, Primary antibody: CSB-PA899967(HDAC3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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