| Объем | 100 мкл |
| Синонимы | Histone deacetylase 8 (HD8) (EC 3.5.1.98), HDAC8, HDACL1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9BY41 |
| Иммуноген | Recombinant Human Histone deacetylase 8 protein (1-377AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
| Примечание | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cardiovascular, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
Western blot
All lanes: Histone deacetylase 8 antibody at 2µg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 42, 30, 18, 32, 29, 16, 17 kDa
Observed band size: 42 kDa
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010244ESR2HU at dilution of 1:100
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Наименование: HDAC8 Antibody.