| Объем | 100 мкг |
| Синонимы | Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2), HIPK1, KIAA0630 MYAK NBAK2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q86Z02 |
| Иммуноген | Recombinant Human Homeodomain-interacting protein kinase 1 protein (1007-1151AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Homeodomain-interacting protein kinase 1 |
| Области исследований | Epigenetics and Nuclear Signaling, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: HIPK1 Antibody, Biotin conjugated.