| Объем | 50 мкл |
| Синонимы | G protein-coupled receptor kinase 4 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P32298 |
| Иммуноген | Fusion protein of human GRK4 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
| Примечание | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin, the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA699224(GRK4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA699224(GRK4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
 |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Hela cells, Jurkat cells, Primary antibody: CSB-PA699224(GRK4 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
 |
| | |
Наименование: GRK4 Antibody.