| Объем | 50 мкл |
| Синонимы | G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6), GRK6, GPRK6 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P43250 |
| Иммуноген | Recombinant Human G protein-coupled receptor kinase 6 protein (1-170AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Rat |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cardiovascular, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: G protein-coupled receptor kinase 6 antibody at 6µg/ml + Rat heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 66, 68, 65 kDa
Observed band size: 66 kDa
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA009927ESR2HU at dilution of 1:100
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Наименование: GRK6 Antibody.