HIST1H2BB AntibodyСпецификацияОбъем | 100 мкл | Синонимы | H2BQ, GL105, H2B.1, H2BFQ, H2BGL105 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P33778 | Иммуноген | Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<br/><br/>Borchert GM,et al. (2010) PLoS One.5(7):e11641.<br/>Pennini ME,et al.(2010) PLoS Pathog.6(7):e1000995.<br/>Lu C,et al. (2010) Sci China Life Sci.53(6):663-8. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Hela and 293 cells using H2B antibody.
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