| Объем | 50 мкг |
| Синонимы | Hairy/enhancer-of-split related with YRPW motif protein 1 (Cardiovascular helix-loop-helix factor 2) (CHF-2) (Class B basic helix-loop-helix protein 31) (bHLHb31) (HES-related repressor protein 1) (Hairy and enhancer of split-related protein 1) (HESR-1) (Hairy-related transcription factor 1) (HRT-1) (hHRT1), HEY1, BHLHB31 CHF2 HERP2 HESR1 HRT1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y5J3 |
| Иммуноген | Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | FITC |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Hairy/enhancer-of-split related with YRPW motif protein 1 |
| Области исследований | Epigenetics and Nuclear Signaling, Cardiovascular |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: HEY1 Antibody, FITC conjugated.