| Объем | 50 мкл |
| Синонимы | hypoxia inducible factor 1, alpha subunit |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q16665 |
| Иммуноген | Fusion protein of human HIF1A |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Примечание | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA968396(HIF1A Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA968396(HIF1A Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
 |
Gel: 8%SDS-PAGE, Lysate: 60 ?g, Lane: Hela cells, Primary antibody: CSB-PA968396(HIF1A Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
 |
| | |
Наименование: HIF1A Antibody.