Объем | 100 мкл |
Синонимы | Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I), HIP1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O00291 |
Иммуноген | Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
Примечание | Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity purified |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: HIP1 antibody at 4µg/ml + A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 117, 111, 114 kDa
Observed band size: 117 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010365ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA010365ESR2HU at dilution of 1:100
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