ALK AntibodyСпецификация| Объем | 50 мкл | | Синонимы | ALK tyrosine kinase receptor | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UM73 | | Иммуноген | Synthetic peptide of human ALK | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:25-1:100 | | Примечание | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Neuroscience,Cancer,Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA847171(ALK Antibody) at dilution 1/25. (Original magnification: ?200)
 | The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA847171(ALK Antibody) at dilution 1/25. (Original magnification: ?200)
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Наименование: ALK Antibody.