MACROD1 Antibody, Biotin conjugatedСпецификацияОбъем | 50 мкг | Синонимы | O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), MACROD1, LRP16 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9BQ69 | Иммуноген | Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Области исследований | Epigenetics and Nuclear Signaling, Cancer, Signal transduction | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 50 мкг | Кат. номер: | CSB-PA860244LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: MACROD1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
|