Объем | 100 мкл |
Синонимы | Insulin-like growth factor I receptor, CD221, IGF1R, kinase IGF1R, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P08069 |
Иммуноген | Peptide sequence around aa.1163~1167/1164~1168 (T-D-Y-Y-R-K) derived from Human IGF-1R . |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.<br/><br/>Li S, et al. (1994) J Biol Chem, 269(51): 32558-64. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Cancer,Developmental biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells using IGF-1R(Ab-1165/1166) Antibody and the same antibody preincubated with blocking peptide.
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