| Объем | 100 мкл |
| Синонимы | ANAPC1, Anaphase promoting complex subunit 1, ANC1, Cyclosome subunit 1, Mitotic checkpoint regulator |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9H1A4 |
| Иммуноген | Synthesized peptide derived from Internal of human APC1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<br/><br/>Joergensen P.M., Gene 262:51-59(2001).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Kraft C., EMBO J. 22:6598-6609(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using APC1 antibody.
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Наименование: ANAPC1 Antibody.