Объем | 100 мкл |
Синонимы | E3 ubiquitin-protein ligase MARCH4 , EC 6.3.2.-, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, MARCH-IV |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9P2E8 |
Иммуноген | Synthesized peptide derived from internal of human MARCH4. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,IHC:1:50-1:100 |
Примечание | <p>E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.<br /><br />Nagase T., DNA Res. 7:65-73(2000).<br />The MGC Project Team, Genome Res. 14:2121-2127(2004).<br />Bartee E., J. Virol. 78:1109-1120(2004).</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology |
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