Объем | 100 мкл |
Синонимы | 100 kDa thyroid hormone receptor associated protein, ARC100, Activator-recruited cofactor 100 kDa component, DRIP100, KIAA0130 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O75448 |
Иммуноген | Synthesized peptide derived from internal of human MED24. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
Примечание | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.<br/><br/>Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).<br/>Rachez C., Genes Dev. 12:1787-1800(1998).<br/>Nagase T., DNA Res. 2:167-174(1995). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using MED24 antibody.
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Immunofluorescence analysis of HUVEC cells, using MED24 antibody.
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