| Объем | 50 мкл |
| Синонимы | Mesoderm posterior protein 2 (Class C basic helix-loop-helix protein 6) (bHLHc6), MESP2, BHLHC6 SCDO2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q0VG99 |
| Иммуноген | Recombinant Human Mesoderm posterior protein 2 protein (218-397AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Mesoderm posterior protein 2 |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Developmental biology |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: MESP2 Antibody.