Объем | 50 мкл |
Синонимы | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P47928 |
Иммуноген | Synthetic peptide of human ID4 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:20-1:100 |
Примечание | DNA-binding protein inhibitor ID-4 is a protein that in humans is encoded by the ID4 gene. Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative (antimorph) HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins . |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA620355(ID4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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