| Объем | 50 мкг |
| Синонимы | Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54), IFIT2, CIG-42 G10P2 IFI54 ISG54 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P09913 |
| Иммуноген | Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | FITC |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Interferon-induced protein with tetratricopeptide repeats 2 |
| Области исследований | Immunology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: IFIT2 Antibody, FITC conjugated.