JMY Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Junction-mediating and -regulatory protein, JMY | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q8N9B5 | Иммуноген | Recombinant Human Junction-mediating and -regulatory protein (708-848AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Junction-mediating and -regulatory protein | Области исследований | Epigenetics and Nuclear Signaling, Cell biology | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA850838LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: JMY Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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