| Объем | 100 мкг |
| Синонимы | Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3), JUP, CTNNG DP3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P14923 |
| Иммуноген | Recombinant Human Junction plakoglobin protein (1-131AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: JUP antibody at 2µg/ml + A431 cells
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 82 kDa
Observed band size: 82 kDa
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA12839A0Rb at dilution of 1:100
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Наименование: JUP Antibody.