Объем | 100 мкл |
Синонимы | Ankyrin repeat domain-containing protein 25, SRC-1-interacting protein, SRC1-interacting protein, Matrix-remodeling-associated protein 3, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q63ZY3 |
Иммуноген | Synthesized peptide derived from internal of human KANK2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.<br/><br/>Nagase T., DNA Res. 7:143-150(2000).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Olsen J.V., Cell 127:635-648(2006).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human heart tissue using KANK2 antibody.
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Immunofluorescence analysis of A549 cells, using KANK2 antibody.
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