| Объем | 50 мкл |
| Синонимы | Matrix metallopeptidase 11 (stromelysin 3) |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P24347 |
| Иммуноген | Synthetic peptide of human MMP11 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Примечание | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cancer,Cardiovascular,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA029613(MMP11 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using CSB-PA029613(MMP11 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 10%SDS-PAGE, Lysate: 60 ?g, Lane 1-2: Human colon tissue, Human ovarian cancer tissue, Primary antibody: CSB-PA029613(MMP11 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Наименование: MMP11 Antibody.