| Объем | 100 мкл |
| Синонимы | matrix metallopeptidase 8 (neutrophil collagenase) |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P22894 |
| Иммуноген | Synthetic peptide of human MMP8 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:1000-1:5000, IHC:1:50-1:200 |
| Примечание | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cancer,Cardiovascular,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA220976(MMP8 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA220976(MMP8 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: HT29 cells, 231 cells, Primary antibody: CSB-PA220976(MMP8 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: MMP8 Antibody.