Объем | 50 мкл |
Синонимы | Krueppel-like factor 4 (Epithelial zinc finger protein EZF) (Gut-enriched krueppel-like factor), KLF4, EZF GKLF |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43474 |
Иммуноген | Recombinant Human Krueppel-like factor 4 protein (30-230AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
Примечание | Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Developmental biology, Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Krueppel-like factor 4 antibody at 5µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 52, 46, 13, 7 kDa
Observed band size: 55 kDa
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Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA012394DSR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA012394DSR2HU at dilution of 1:100
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