| Объем | 50 мкг |
| Синонимы | Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP), Irf8, Icsbp Icsbp1 |
| Клональность | Polyclonal Antibody |
| Организм | Mouse |
| uniprot | P23611 |
| Иммуноген | Recombinant Mouse Interferon regulatory factor 8 protein (1-424AA) |
| Источник | Rabbit |
| Видовая специфичность | Mouse |
| Применение | ELISA, WB, Recommended dilution: WB:1:500-1:2000 |
| Примечание | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Epigenetics and Nuclear Signaling, Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Irf8 antibody at 2µg/ml + Raji whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa
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Наименование: Irf8 Antibody.