IRS1 (Ab-636) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | IRS-1, IRS1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P35568 | | Иммуноген | Peptide sequence around aa.634~638 (P-M-S-P-K) derived from Human IRS-1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 | | Примечание | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit <br/><br/>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A, 98(8): 4640-4645<br/>Tzatsos A, et al. (2006) Mol Cell Biol, 26(1): 63-76<br/>Kadowaki T, et al. (2000) J Clin Invest, 106(4): 459-465<br/>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A, 98(8): 4640-4645<br/>Szanto I, et al. (2000) Proc Natl Acad Sci U S A, 97(5): 2355-2360<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Cancer,Cardiovascular,Tags & Cell Markers,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells using IRS-1(Ab-636) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1(Ab-636) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 | Immunofluorescence staining of methanol-fixed Hela cells using IRS-1(Ab-636) Antibody.
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Наименование: IRS1 (Ab-636) Antibody.