Объем | 100 мкл |
Синонимы | Potassium voltage-gated channel subfamily A member 5, Voltage-gated potassium channel subunit Kv1.5, HK2, HPCN1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P22460 |
Иммуноген | Synthesized peptide derived from internal of human KCNA5. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.<br/><br/>Tamkun M.M., FASEB J. 5:331-337(1991).<br/>Philipson L.H., Proc. Natl. Acad. Sci. U.S.A. 88:53-57(1991).<br/>Curran M.E., Genomics 12:729-737(1992).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience,Cancer,Cardiovascular,Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using KCNA5 antibody.
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