JMY Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	Junction-mediating and -regulatory protein, JMY
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8N9B5
Иммуноген	Recombinant Human Junction-mediating and -regulatory protein (708-848AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Junction-mediating and -regulatory protein
Области исследований	Epigenetics and Nuclear Signaling, Cell biology
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA850838LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: JMY Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).