Объем | 100 мкл |
Синонимы | EC 2.3.1.48, HBO1, HBOA, MYST histone acetyltransferase 2, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95251 |
Иммуноген | Synthesized peptide derived from internal of human MYST2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
Примечание | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.<br/><br/>Iizuka M., J. Biol. Chem. 274:23027-23034(1999).<br/>Sharma M., J. Biol. Chem. 275:35200-35208(2000).<br/>Olsen J.V., Cell 127:635-648(2006).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using MYST2 antibody.
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Immunofluorescence analysis of HUVEC cells, using MYST2 antibody.
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