NEIL1 Antibody, FITC conjugated

Спецификация

Объем	50 мкг
Синонимы	Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1), NEIL1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q96FI4
Иммуноген	Recombinant Human Endonuclease 8-like 1 protein (2-390AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Epigenetics and Nuclear Signaling
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA846619LC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: NEIL1 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).