KLC1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | kinesin light chain 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q07866 | Иммуноген | Fusion protein of human KLC1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 | Примечание | Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Neuroscience,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA907505(KLC1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA907505(KLC1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: Lovo cells, Primary antibody: CSB-PA907505(KLC1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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