KRT10 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Keratin type I cytoskeletal 10, Cytokeratin-10, CK-10, K10, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P13645 | Иммуноген | Synthesized peptide derived from human Keratin 10. | Источник | Rabbit | Видовая специфичность | Human, Rat | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | Примечание | This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.<br/><br/>XM Zhou, J. Biol. Chem., Oct 1988, 263: 15584 - 15589.<br/>Felix B. M篓绛秎er, Hum. Mol. Genet., Apr 2006, 15: 1133 - 1141.<br/>J Reichelt, J. Cell Sci., Sep 1997, 110: 2175.<br/>BP Korge, PNAS, Feb 1992, 89: 910.<br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence analysis of A549 cells, using Keratin 10 antibody.
| Western blot analysis of extracts from HeLa cells, using Keratin 10 antibody.
| Western blot analysis of extracts from COS7 cells and 3T3 cells using Keratin 10 antibody. The lane on the left is treated with synthesized peptide.
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