KRT5 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Keratin type II cytoskeletal 5, Cytokeratin-5, CK-5, K5, 58 kDa cytokeratin | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P13647 | | Иммуноген | Synthesized peptide derived from human Keratin 5. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.<br/><br/>Bettina Peters, Mol. Biol. Cell, Jun 2001, 12: 1775.<br/>J Casatorres, J. Biol. Chem., Aug 1994, 269: 20489 - 20496.<br/>Karin M篓绛秎er-Decker, Am. J. Pathol., Feb 2005, 166: 575 - 584.<br/>Angel Ram篓鐚篹z, Genetics, May 2001, 158: 341.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Keratin 5 antibody.
 | Western blot analysis of extracts from HepG2 cells, using Keratin 5 antibody.
 | Western blot analysis of extracts from 293 cells (Lane 2) and HepG2 cells (Lane 3), using Keratin 5 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: KRT5 Antibody.