KRT16 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Keratin type I cytoskeletal 16, Cytokeratin-16, CK-16, K16, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P08779 | Иммуноген | Synthesized peptide derived from human Keratin 16. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.<br/><br/>Qian Wang, J. Virol., Jan 2004, 78: 821 - 833. RD Paladini, <br/>RD Paladini, J. Cell Biol., Feb 1996, 132: 381.<br/>M.K. Shamsher, Hum. Mol. Genet., Oct 1995, 4: 1875 - 1881.<br/>Ying-Nai Wang, Mol. Pharmacol., Jan 2006, 69: 85 - 98.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells, using Keratin 16 antibody.
| Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Keratin 16 antibody.
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