LMP2 Antibody, Biotin conjugatedСпецификация| Объем | 50 мкг | | Синонимы | Latent membrane protein 2 (Terminal protein), LMP2 | | Клональность | Polyclonal Antibody | | Организм | Epstein-Barr virus | | uniprot | P13285 | | Иммуноген | Recombinant Epstein-Barr virus Latent membrane protein 2 protein (1-147AA) | | Источник | Rabbit | | Видовая специфичность | Epstein-Barr virus | | Применение | ELISA | | Примечание | Isoform LMP2A maintains EBV latent infection of B-lymphocyte, by preventing lytic reactivation of the virus in response to surface immunoglobulin (sIg) cross-linking. Acts like a dominant negative inhibitor of the sIg-associated protein tyrosine kinases, LYN and SYK. Also blocks translocation of the B-cell antigen receptor (BCR) into lipid rafts, preventing the subsequent signaling and accelerated internalization of the BCR upon BCR cross-linking. Serves as a molecular scaffold to recruit SYK, LYN and E3 protein-ubiquitin ligases, such as ITCH and NEDD4L, leading to ubiquitination and potential degradation of both tyrosines kinases. Possesses a constitutive signaling activity in non-transformed cells, inducing bypass of normal B lymphocyte developmental checkpoints allowing immunoglobulin-negative cells to colonize peripheral lymphoid organs. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Latent membrane protein 2 | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA321086HD01EFA | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: LMP2 Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
|
