Объем | 100 мкл |
Синонимы | acyltransferase-like 1, EC 2.3.1.-, PCAT2, PCATA, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q7L5N7 |
Иммуноген | Synthesized peptide derived from internal of human LPCAT2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>The German cDNA consortium, Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells and HT-29 cells, using LPCAT2 antibody.
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