| Объем | 100 мкл |
| Синонимы | EC 2.7.1.112, EC 2.7.10.1, Leukocyte tyrosine kinase receptor precursor, Protein tyrosine kinase-1, TYK1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P29376 |
| Иммуноген | Synthesized peptide derived from internal of human LTK. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.<br/><br/>Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).<br/>Krolewski J.J., EMBO J. 10:2911-2919(1991).<br/>Maru Y., Oncogene Res. 5:199-204(1990).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using LTK antibody.
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Наименование: LTK Antibody.