LRAT AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Lecithin retinol acyltransferase, EC 2.3.1.135, Phosphatidylcholine--retinol O-acyltransferase, LRAT, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O95237 | Иммуноген | Synthesized peptide derived from internal of human LRAT. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium, due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.<br/><br/>Ruiz A., J. Biol. Chem. 274:3834-3841(1999).<br/>Mondal M.S., Biochemistry 39:5215-5220(2000).<br/>Thompson D.A., Nat. Genet. 28:123-124(2001).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Neuroscience,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO205 cells, using LRAT antibody.
 | Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using LRAT antibody.
 | Immunofluorescence analysis of HUVEC cells, using LRAT antibody.
 | | |
Информация для заказа |