Объем | 100 мкл |
Синонимы | Nuclear mitotic apparatus protein 1, NuMA protein, SP-H antigen, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14980 |
Иммуноген | Synthesized peptide derived from internal of human NUMA1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
Примечание | Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.<br/><br/>Yang C.H., J. Cell Biol. 116:1303-1317(1992).<br/>Compton D.A., J. Cell Biol. 116:1395-1408(1992).<br/>Maekawa T., J. Cell Sci. 105:589-600(1993).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from A549 cells, using NUMA1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human testis tissue using NUMA1 antibody.
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