Объем | 100 мкл |
Синонимы | MEX67, TAP, Tip-associated protein, mRNA export factor TAP, nuclear RNA export factor 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UBU9 |
Иммуноген | Synthesized peptide derived from N-terminal of human NXF1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.<br/><br/>Braun I.C., EMBO J. 18:1953-1965(1999).<br/>Kang Y., Genes Dev. 13:1126-1139(1999).<br/>Bear J., Mol. Cell. Biol. 19:6306-6317(1999).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, Jurkat cells and HeLa cells, using NXF1 antibody.
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